Universal RHD genotyping in fetuses
- PMID: 18390495
- PMCID: PMC2292275
- DOI: 10.1136/bmj.39533.358252.BE
Universal RHD genotyping in fetuses
Abstract
Is effective, and could dramatically reduce unnecessary anti-RhD prophylaxis
Conflict of interest statement
Competing interests: None declared.
Comment on
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Effect of high throughput RHD typing of fetal DNA in maternal plasma on use of anti-RhD immunoglobulin in RhD negative pregnant women: prospective feasibility study.BMJ. 2008 Apr 12;336(7648):816-8. doi: 10.1136/bmj.39518.463206.25. Epub 2008 Apr 3. BMJ. 2008. PMID: 18390496 Free PMC article.
References
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- Minon JM, Gerard C, Senterre JM, Schaaps JP, Foidart JM. Routine fetal RHD genotyping with maternal plasma: a four-year experience in Belgium. Transfusion 2008;48:373-81. - PubMed
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- Rouillac-Le Sciellour C, Puillandre P, Gillot R, Baulard C, Métral S, Le Van Kim C, et al. Large-scale pre-diagnosis study of fetal RHD genotyping by PCR on plasma DNA from RhD-negative pregnant women. Mol Diagn 2004;8:23-31. - PubMed
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- Finning K, Martin P, Summers J, Daniels G. Fetal genotyping for the K (Kell) and Rh C, c, and E blood groups on cell-free fetal DNA in maternal plasma. Transfusion 2007;47:2126-33. - PubMed
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- Finning K, Martin P, Summers J, Massey E, Poole G, Daniels G. Effect of high throughput RHD typing of fetal DNA in maternal plasma on use of anti-RhD immunoglobulin in RhD negative pregnant women: prospective trial. BMJ 2008; doi: 10.1136/bmj.39518.463206.25 - DOI - PMC - PubMed
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