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Editorial
. 2008 Apr;93(4):1183-5.
doi: 10.1210/jc.2008-0426.

Caveolin-1: a new locus for human lipodystrophy

Abhimanyu Garg, Anil K Agarwal
Editorial

Caveolin-1: a new locus for human lipodystrophy

Abhimanyu Garg et al. J Clin Endocrinol Metab. 2008 Apr.
No abstract available

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Figures

Figure 1
Figure 1
Role of CAV1 in adipocyte. Caveolae are formed from lipid rafts on the cell surface, which include cholesterol (yellow symbols), glycosphingolipids (green symbols), and CAV1. Caveolae could be endocytosed and can form caveolin-1-containing vesicles. CAV1 has also been found to be associated with lipid droplets in adipocytes. However, whether CAV1-containing vesicles directly merge with lipid droplets or CAV1 is incorporated directly within the endoplasmic reticulum (ER) during formation of lipid droplet still remains unclear. Shown also on the lipid droplets are various PAT domain-containing proteins (blue triangles and pink squares) that decorate the lipid droplet including the well-known marker perilipin (shown as green circles).
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