Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 Jun;52(6):2226-7.
doi: 10.1128/AAC.00414-07. Epub 2008 Apr 7.

In vitro activities of linezolid against clinical isolates of Mycobacterium tuberculosis complex isolated in Taiwan over 10 years

Tsi-Shu Huang  1 , Yung-Ching Liu, Cheng-Len Sy, Yao-Shen Chen, Hui-Zin Tu, Bao-Chen Chen
Affiliations

In vitro activities of linezolid against clinical isolates of Mycobacterium tuberculosis complex isolated in Taiwan over 10 years

Tsi-Shu Huang et al. Antimicrob Agents Chemother. 2008 Jun.

Abstract

Significant increases in the MIC(90)s of linezolid in multidrug-resistant Mycobacterium tuberculosis isolates were seen between the baseline period of 2001 to 2003 (0.5 microg/ml) and 2004 (2 microg/ml). The MICs were 4 microg/ml in three strains. Both fluoroquinolones (except levofloxacin) and kanamycin were found to have statistically significant degrees of concordance with linezolid.

PubMed Disclaimer

References

    1. Alcalá, L., M. J. Ruiz-Serrano, C. Pérez-Fernández Turégano, D. García De Viedma, M. Díaz-Infantes, M. Marín-Arriaza, and E. Bouza. 2003. In vitro activities of linezolid against clinical isolates of Mycobacterium tuberculosis that are susceptible or resistant to first-line antituberculous drugs. Antimicrob. Agents Chemother. 47:416-417. - PMC - PubMed
    1. Centers for Disease Control. 2004. Statistics of communicable diseases and surveillance report in Taiwan area, 2003. Centers for Disease Control, Taipei, Taiwan.
    1. Escribano, I., J. C. Rodriguez, B. Llorca, E. Garcia-Pachon, M. Ruiz, and G. Royo. 2007. Importance of the efflux pump systems in the resistance of Mycobacterium tuberculosis to fluoroquinolones and linezolid. Chemotherapy 53:397-401. - PubMed
    1. Hilderand, D. K., J. D. Laingand, and H. Rosenthal. 1977. Prediction analysis of cross classifications, p. 55-56. In J. Neter, W. Wasserman, and G. G. Whitmore (ed.), Applied statistics. John Wiley & Sons, New York, NY.
    1. Hsueh, P. R., Y. C. Liu, J. So, C. Y. Liu, P. C. Yang, and K. T. Luh. 2006. Mycobacterium tuberculosis in Taiwan. J. Infect. 52:77-85. - PubMed

Publication types

MeSH terms