Sorting out small RNAs
- PMID: 18394983
- DOI: 10.1016/j.cell.2008.03.015
Sorting out small RNAs
Abstract
Small RNAs carry out their functions by guiding Argonaute (AGO) proteins to their targets. Diverse types of small RNAs and multiple AGO proteins exist in most eukaryotic species, but how small RNAs are sorted into specific AGO complexes remains unclear. Two papers in this issue (Mi et al., 2008; Montgomery et al., 2008) now reveal the importance of the 5' terminal nucleotide of the small RNA in the sorting process in Arabidopsis.
Comment on
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Sorting of small RNAs into Arabidopsis argonaute complexes is directed by the 5' terminal nucleotide.Cell. 2008 Apr 4;133(1):116-27. doi: 10.1016/j.cell.2008.02.034. Epub 2008 Mar 13. Cell. 2008. PMID: 18342361 Free PMC article.
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Specificity of ARGONAUTE7-miR390 interaction and dual functionality in TAS3 trans-acting siRNA formation.Cell. 2008 Apr 4;133(1):128-41. doi: 10.1016/j.cell.2008.02.033. Epub 2008 Mar 13. Cell. 2008. PMID: 18342362
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