Cancer: inappropriate expression of stem cell programs?
- PMID: 18397746
- DOI: 10.1016/j.stem.2008.03.014
Cancer: inappropriate expression of stem cell programs?
Abstract
Cancer stem cells (CSCs) are a subpopulation of cancer cells that possess characteristics, including self-renewal, associated with normal stem cells. In this issue of Cell Stem Cell, Wong et al. (2008) define a core embryonic stem cell (ESC)-like gene expression program that may be important for CSC function in multiple epithelial cancers.
Comment on
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Module map of stem cell genes guides creation of epithelial cancer stem cells.Cell Stem Cell. 2008 Apr 10;2(4):333-44. doi: 10.1016/j.stem.2008.02.009. Cell Stem Cell. 2008. PMID: 18397753 Free PMC article.
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