Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2008 Jun;22(6):1435-9.
doi: 10.1007/s00464-008-9904-1. Epub 2008 Apr 9.

Prospective randomized comparison of laparoscopic versus open adrenalectomy for sporadic pheochromocytoma

Guido A M Tiberio  1 , Gian Luca Baiocchi, Luca Arru, Claudia Agabiti Rosei, Simona De Ponti, Albert Matheis, Damiano Rizzoni, Stefano M Giulini
Affiliations
Free article
Randomized Controlled Trial

Prospective randomized comparison of laparoscopic versus open adrenalectomy for sporadic pheochromocytoma

Guido A M Tiberio et al. Surg Endosc. 2008 Jun.
Free article

Abstract

Background: Laparoscopic adrenalectomy for pheochromocytoma remains subject of debate, owing to the systemic consequences of pneumoperitoneum in patients with catecholamine-secreting tumors.

Methods: A prospective randomized study was conducted (2000-2006), evaluating cardiovascular instability during open (n = 9, group A) or laparoscopic (n = 13, group B) adrenalectomy for pheochromocytoma. Haemodynamic parameters were recorded by invasive monitoring.

Results: Haemodynamic instability was observed in 3/9 (group A) and 6/13 patients (group B), with a mean of 1.8 and 2.2 hypertensive peaks per patient (p = n.s.). Blood loss (164 +/- 94 cc versus 48 +/- 36 cc, p < 0.05) and operative time (180 +/- 40 versus 158 +/- 45 min, p = n.s.) favored laparoscopic procedures. Postoperative morbidity and mortality were nil. Hospital stay was shorter in group B (p < 0.05). Long-term follow-up was always normal.

Conclusions: Laparoscopic approach for pheochromocytoma can be as safe as open surgery; intraoperative haemodynamic instability, although usually controlled with success, remains a source of concern.

PubMed Disclaimer

References

    1. Surg Endosc. 1999 Jan;13(1):35-9 - PubMed
    1. World J Surg. 1996 Sep;20(7):762-8; discussion 768 - PubMed
    1. Surg Endosc. 2002 Jan;16(1):100-2 - PubMed
    1. Chir Ital. 2005 May-Jun;57(3):273-81 - PubMed
    1. N Engl J Med. 1992 Oct 1;327(14):1033 - PubMed

Publication types

MeSH terms

LinkOut - more resources