Basophils are back!
- PMID: 18400194
- DOI: 10.1016/j.immuni.2008.03.010
Basophils are back!
Abstract
In this issue of Immunity, Tsujimura et al. (2008) report that the release of platelet-activating factor by basophils stimulated with immunoglobulin G1 (IgG1)-antigen immune complexes contributes substantially to the expression of an IgG1-dependent alternative pathway of systemic anaphylaxis in mice.
Comment on
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Basophils play a pivotal role in immunoglobulin-G-mediated but not immunoglobulin-E-mediated systemic anaphylaxis.Immunity. 2008 Apr;28(4):581-9. doi: 10.1016/j.immuni.2008.02.008. Epub 2008 Mar 13. Immunity. 2008. PMID: 18342553
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