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Review
. 2008 Jan;62(1):1-33.
doi: 10.1007/s11418-007-0166-3. Epub 2007 Sep 5.

Bioactive cyclobutane-containing alkaloids

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Review

Bioactive cyclobutane-containing alkaloids

Valery M Dembitsky. J Nat Med. 2008 Jan.

Abstract

The present review describes research on novel natural cyclobutane-containing alkaloids and synthetic compounds isolated from terrestrial and marine species. More than 210 compounds have been confirmed to show antimicrobial, antibacterial, anticancer, and other activities. Structures, origins, biosynthesis, photodimerization, and biological activities of a selection of cyclobutane-containing alkaloids and selected synthetic analogs of natural alkaloids are reviewed.

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