Bioactive cyclobutane-containing alkaloids
- PMID: 18404338
- DOI: 10.1007/s11418-007-0166-3
Bioactive cyclobutane-containing alkaloids
Abstract
The present review describes research on novel natural cyclobutane-containing alkaloids and synthetic compounds isolated from terrestrial and marine species. More than 210 compounds have been confirmed to show antimicrobial, antibacterial, anticancer, and other activities. Structures, origins, biosynthesis, photodimerization, and biological activities of a selection of cyclobutane-containing alkaloids and selected synthetic analogs of natural alkaloids are reviewed.
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