Cloning and functional expression of a TEA-sensitive A-type potassium channel from rat brain
- PMID: 1840526
- DOI: 10.1016/0014-5793(91)80119-n
Cloning and functional expression of a TEA-sensitive A-type potassium channel from rat brain
Abstract
A rat brain cDNA (Raw3) related to the Drosophila Shaw K+ channel family has been characterized. Raw3 cRNA leads to the formation of TEA-insensitive, fast inactivating (A-type) K+ channels when injected into Xenopus laevis oocytes. Raw3 channels have markedly different properties from the previously cloned rat A-type K+ channel RCK4, Raw3 channels operate in the positive voltage range.
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