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. 1998 Feb;9(2):62-7.
doi: 10.1016/s1043-2760(98)00019-8.

Insights into the development of polycystic ovary syndrome (PCOS) from studies of prenatally androgenized female rhesus monkeys

D H Abbott  1 , D A Dumesic, J R Eisner, R J Colman, J W Kemnitz
Affiliations

Insights into the development of polycystic ovary syndrome (PCOS) from studies of prenatally androgenized female rhesus monkeys

D H Abbott et al. Trends Endocrinol Metab. 1998 Feb.

Abstract

The developmental pathophysiology of polycystic ovary syndrome (PCOS) is unknown. However, prenatally androgenized female rhesus monkeys exhibit ovarian and endocrinological features that mimic those found in women with PCOS. Thus, prenatal androgen excess may provide an etiology for hyperandrogenism and anovulation in adulthood.

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