Comparative Study
doi: 10.1093/oxfordjournals.molbev.a040663.
A Y-chromosomal DNA fragment is conserved in human and chimpanzee
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- PMID: 1840631
- DOI: 10.1093/oxfordjournals.molbev.a040663
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Comparative Study
A Y-chromosomal DNA fragment is conserved in human and chimpanzee
Mol Biol Evol.
1991 Jul.
Abstract
A human male-specific Y-chromosomal DNA fragment (lambda YH2D6) has been isolated. By deletion-mapping analysis, 2D6 has been localized to the euchromatic portion of the long arm (Yq11) of the human Y chromosome. Among great apes, this fragment was found to be conserved in male chimpanzee but was lacking in male gorilla and male orangutan. No homologous fragments were detected in females of orangutan, gorilla, chimpanzee, or human. Nucleotide sequence analysis indicated the presence of partial-Alu-elements and of sequences similar to the GATA repeats of the snake Bkm sequence.
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