Poised polymerases: on your mark...get set...go!
- PMID: 18406322
- DOI: 10.1016/j.molcel.2008.03.001
Poised polymerases: on your mark...get set...go!
Abstract
Recent global analyses have determined that many Drosophila and human genes have engaged polymerase molecules trapped immediately downstream of promoters. These results strongly implicate RNA polymerase II elongation control as a major regulator of differentiation and development.
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