Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 Aug;103(1-3):143-50.
doi: 10.1016/j.schres.2008.02.016. Epub 2008 Apr 14.

Duration of early maternal separation and prediction of schizotypal symptoms from early adolescence to midlife

Affiliations

Duration of early maternal separation and prediction of schizotypal symptoms from early adolescence to midlife

Deidre M Anglin et al. Schizophr Res. 2008 Aug.

Abstract

Early childhood experiences influence the capacity for healthy social and emotional development. The present study uses longitudinal data to determine whether early maternal separation predicted the subsequent development of schizotypal personality disorder (SPD) symptoms assessed repeatedly from early adolescence over the following 20 years. Within this community sample (N=766), multilevel linear regression analyses revealed the duration of separation from mother in the first 2 years of life predicted elevated SPD symptoms. This relationship was specific to children with mother-reported early angry emotional behavior. These results provide support for the role of early childhood psychosocial risk factors in the development of subsequent schizophrenia spectrum symptoms in emotionally vulnerable children.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Schizotypal personality disorder symptoms from age 10 to 35 for those with and without a) early separation of 8 weeks duration from mother and b) angry temperament

References

    1. Agid O, Shapira B, Zislin J, Ritsner M, Hanin B, Murad H, Troudart T, Bloch M, Heresco-Levy U, Lerer B. Environment and vulnerability to major psychiatric illness: a case control study of early parental loss in major depression, bipolar disorder and schizophrenia. Mol Psychiatry. 1999;4(2):163–172. - PubMed
    1. Ainsworth MD. Attachment as related to mother-infant interaction. In: Rosenblatt J, Hinde RA, Beer C, Busnel M, editors. Advances in the study of behavior. 15. Vol. 1. New York: Academic Press; 1979.
    1. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. Fourth edition. Washington, D. C: Author; 1994. revised.
    1. Berry K, Barrowclough C, Wearden A. A review of the role of adult attachment style in psychosis: unexplored issues and questions for further research. Clin Psychol Rev. 2007;27(4):458–475. - PubMed
    1. Bowlby J. Attachment. New York: Basic Books; 1969. Attachment and Loss. Vol. 1.

Publication types

MeSH terms