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. 2008 May;131(5):407-13.
doi: 10.1085/jgp.200709926. Epub 2008 Apr 14.

Antibody-based validation of CNS ion channel drug targets

Kenneth J Rhodes  1 , James S Trimmer
Affiliations

Antibody-based validation of CNS ion channel drug targets

Kenneth J Rhodes et al. J Gen Physiol. 2008 May.
No abstract available

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Figures

Figure 1.
Figure 1.
(Left panels) Double immunofluorescence staining of brain sections from wild-type and BKα knockout mice. Image shows the hippocampal field stained with mouse monoclonal anti-BKα L6/60 and anti-Kv1.4 K13/31 antibodies. Isotype-specific secondary antibodies were used to visualize bound monoclonal antibodies. Right panel shows an immunoblot performed with L6/60 on crude brain membranes from rats (RBM) and from wild-type (MBM-WT) and BKα knockout (MBM-BKα KO) mice.
See this image and copyright information in PMC

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