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Review
. 2008 May 15;148C(2):127-32.
doi: 10.1002/ajmg.c.30169.

Genetics of post-traumatic stress disorder: informing clinical conceptualizations and promoting future research

Nicole R Nugent  1 , Ananda B Amstadter, Karestan C Koenen
Affiliations
Review

Genetics of post-traumatic stress disorder: informing clinical conceptualizations and promoting future research

Nicole R Nugent et al. Am J Med Genet C Semin Med Genet. .

Abstract

The purpose of this article is to provide an overview of genetic research involving post-traumatic stress disorder (PTSD). First, we summarize evidence for genetic influences on PTSD from family investigations. Second, we discuss the distinct contributions to our understanding of the genetics of PTSD permitted by twin studies. Finally, we summarize findings from molecular genetic studies, which have the potential to inform our understanding of underlying biological mechanisms for the development of PTSD.

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Figures

Figure 1
Figure 1
Prevalence of post-hurricane PTSD by SLC6A4 genotype, level of social support, and level of hurricane exposure in adults exposed to 2004 Florida Hurricanes.
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