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. 2008 Jun;46(6):2099-101.
doi: 10.1128/JCM.00194-08. Epub 2008 Apr 16.

Outbreak of OXY-2-Producing Klebsiella oxytoca in a renal transplant unit

Mariela Soledad Zárate  1 , Ana C Gales, Renata C Picão, Gervasio Soler Pujol, Alejandra Lanza, Jorgelina Smayevsky
Affiliations

Outbreak of OXY-2-Producing Klebsiella oxytoca in a renal transplant unit

Mariela Soledad Zárate et al. J Clin Microbiol. 2008 Jun.

Abstract

We describe a Klebsiella oxytoca infection outbreak in a renal transplant unit that involved seven patients. All strains belonged to a single pulsed-field gel electrophoresis pattern and were resistant to amoxicillin-clavulanate, cefuroxime, piperacillin-tazobactam, and aztreonam but susceptible to ceftriaxone, ceftazidime, cefepime, and imipenem. Chromosomal beta-lactamase hyperproduction was caused by a point mutation in the bla(OXY-2) gene promoter region.

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Figures

FIG. 1.
FIG. 1.
PFGE patterns of SpeI-digested chromosomal DNA restriction fragments from K. oxytoca isolates resolved in 1% SeaKem Gold agarose. Lanes 1 and 11, molecular weight standards of lambda ladder. Lane 2, strain 1 (PFGE pattern A); lane 3, strain X (quality control strain); lane 4, strain 2 (PFGE pattern A); lane 5, strain 3 (PFGE pattern A); lane 6, strain 4 (PFGE pattern A); lane 7, strain 5 (PFGE pattern A); lane 8, strain 6 (PFGE pattern A); lane 9, strain 7 (PFGE pattern A); and lane 10, strain U (quality control strain).
See this image and copyright information in PMC

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