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Review
. 2008 Jul;84(1):149-52.
doi: 10.1038/clpt.2008.75. Epub 2008 Apr 16.

Probing the mind: anesthesia and neuroimaging

M T Alkire  1
Affiliations
Review

Probing the mind: anesthesia and neuroimaging

M T Alkire. Clin Pharmacol Ther. 2008 Jul.

Abstract

In 1947, a second power of anesthesia was described: "With anesthetic agents we seem to have a tool for producing and holding at will, and at little risk, different levels of consciousness--a tool that promises to be of great help in studies of mental phenomena." In 1995, anesthetic manipulation was coupled with neuroimaging, paving the way for detailed assessments of the relationship between the structure and the functioning of the brain. Anesthesia combined with neuroimaging thus provides a unique tool for investigating the neural correlates of human cognition.

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