Studying posttranslational modifications by in-cell NMR
- PMID: 18420137
- DOI: 10.1016/j.chembiol.2008.03.008
Studying posttranslational modifications by in-cell NMR
Abstract
Functional in vivo investigation of posttranslational modifications is a problem that a number of analytical techniques are trying to tackle. Below, we briefly discuss the breakthroughs and challenges in placing NMR spectroscopy on the map, as illustrated by a recent report by Selenko et al. (2008).
Comment on
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In situ observation of protein phosphorylation by high-resolution NMR spectroscopy.Nat Struct Mol Biol. 2008 Mar;15(3):321-9. doi: 10.1038/nsmb.1395. Epub 2008 Feb 24. Nat Struct Mol Biol. 2008. PMID: 18297086
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