Review
[Regenerative cell therapy of the type I diabetes mellitus and its complications]
[Article in
Russian]
- PMID: 18421908
Item in Clipboard
Review
[Regenerative cell therapy of the type I diabetes mellitus and its complications]
[Article in
Russian]
Vestn Ross Akad Med Nauk.
2008.
Abstract
This review describes up-to-date concepts of the type I diabetes mellitus pathogenesis and its complications. The leading role of the immune system malfunction in pancreatic islet of Langerhans and in vessel wall regeneration impairment is emphasized. It is suggested, that cell therapy of the type I diabetes mellitus with pancreatic islet and bone marrow cell transplantation promote beta-cell regeneration due to normalization of intracellular interaction in these tissues and immune homeostasis in whole organism.
Similar articles
-
Stem cell-based treatments for Type 1 diabetes mellitus: bone marrow, embryonic, hepatic, pancreatic and induced pluripotent stem cells.Diabet Med. 2012 Jan;29(1):14-23. doi: 10.1111/j.1464-5491.2011.03433.x. Diabet Med. 2012. PMID: 21883442 Review.
-
Immunogenicity of β-cells for autologous transplantation in type 1 diabetes.Pharmacol Res. 2015 Aug;98:60-8. doi: 10.1016/j.phrs.2015.03.003. Epub 2015 Mar 20. Pharmacol Res. 2015. PMID: 25801943 Review.
-
[Islet transplantation, stem cell transfer and regenerative therapy in diabetes mellitus].Dtsch Med Wochenschr. 2006 Apr 21;131(16):903-6. doi: 10.1055/s-2006-939867. Dtsch Med Wochenschr. 2006. PMID: 16625486 German. No abstract available.
-
[Correction of autoimmune mechanisms underlying the development of type I diabetes mellitus by methods of cell therapy].Vestn Ross Akad Med Nauk. 2010;(9):34-42. Vestn Ross Akad Med Nauk. 2010. PMID: 21089446 Review. Russian.
-
Rehabilitation of adaptive immunity and regeneration of beta cells.Trends Biotechnol. 2006 Nov;24(11):516-22. doi: 10.1016/j.tibtech.2006.08.007. Epub 2006 Sep 11. Trends Biotechnol. 2006. PMID: 16963140 Review.