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. 2008 Jul;80(1):91-2.
doi: 10.1016/j.eplepsyres.2008.03.002.

Thrombocytopenia during levetiracetam therapy

A Meschede  1 , U Runge, M Sabolek
Affiliations

Thrombocytopenia during levetiracetam therapy

A Meschede et al. Epilepsy Res. 2008 Jul.

Abstract

A 64-year-old patient with symptomatic epilepsy developed thrombocytopenia during treatment with levetiracetam (LEV). As no other medical reason could be evaluated, a medication side effect was postulated. The only new drugs were valproic acid (since 3 weeks) and levetiracetam (since 3 days). After valproic acid medication was ended, thrombocytopenia did not improve and even worsened further. Finally levetiracetam administration was ended and trombocytopenia resolved rapidly and completely within few days.

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