doi: 10.1002/0471142905.hg0109s09.
Overview of linkage analysis in complex traits
Affiliations
- PMID: 18428239
- DOI: 10.1002/0471142905.hg0109s09
Item in Clipboard
Overview of linkage analysis in complex traits
Curr Protoc Hum Genet.
2001 May.
Abstract
The goal of this unit is to instruct the reader on the general approaches now available for mapping complex disease. The term complex genetic disease refers to a trait phenotype with an unknown mode of inheritance. The goal of this unit is to instruct the reader on the general approaches now available for mapping complex disease.
Similar articles
-
How to model a complex trait. 1. General considerations and suggestions.Hum Hered. 2003;55(4):202-10. doi: 10.1159/000073204. Hum Hered. 2003. PMID: 14566098 Review.
-
Empirical evaluation of genome scans for linkage of a quantitative trait associated with a complex disorder.Genet Epidemiol. 1997;14(6):927-32. doi: 10.1002/(SICI)1098-2272(1997)14:6<927::AID-GEPI61>3.0.CO;2-N. Genet Epidemiol. 1997. PMID: 9433602
-
A variance component approach to dichotomous trait linkage analysis using a threshold model.Genet Epidemiol. 1997;14(6):987-92. doi: 10.1002/(SICI)1098-2272(1997)14:6<987::AID-GEPI71>3.0.CO;2-G. Genet Epidemiol. 1997. PMID: 9433612
-
Covariate effects on linkage and association using a general pair method.Genet Epidemiol. 1997;14(6):1059-64. doi: 10.1002/(SICI)1098-2272(1997)14:6<1059::AID-GEPI83>3.0.CO;2-G. Genet Epidemiol. 1997. PMID: 9433624
-
Linkage mapping of quantitative trait loci in humans: an overview.Ann Hum Genet. 2002 Nov;66(Pt 5-6):431-8. doi: 10.1017/S0003480002001240. Ann Hum Genet. 2002. PMID: 12485475 Review.
Cited by
-
Complex Genetic Disorders: Evaluating When Genetic Research Findings Are Applicable for Genetic Counseling Practice.J Genet Couns. 1999 Apr;8(2):73-84. doi: 10.1023/A:1022843530795. J Genet Couns. 1999. PMID: 26141971
MeSH terms
LinkOut - more resources
Full Text Sources
