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. 2001 May:Chapter 4:Unit4.8.
doi: 10.1002/0471142905.hg0408s14.

Chromosome microdissection

P Meltzer  1 , M Bittner
Affiliations

Chromosome microdissection

P Meltzer et al. Curr Protoc Hum Genet. 2001 May.

Abstract

This unit describes chromosome microdissection methodologies that are useful in both clinical and research laboratories. In combination with FISH, region-specific probes can be made to determine the origin of marker chromosomes. Another application of the microdissection technology is in the generation of regionspecific cDNA libraries, known as microdissection-mediated cDNA capture.

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