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Review
. 2008 Apr;109(3-5):314-22.
doi: 10.1016/j.jsbmb.2008.03.011. Epub 2008 Mar 8.

Thyroid hormone and myocardial ischaemia

Constantinos Pantos  1 , Iordanis Mourouzis, Christodoulos Xinaris, Dennis V Cokkinos
Affiliations
Review

Thyroid hormone and myocardial ischaemia

Constantinos Pantos et al. J Steroid Biochem Mol Biol. 2008 Apr.

Abstract

Thyroid hormone has various effects on the cardiovascular system and its effects on cardiac contractility, heart rhythm and vascular function has long been recognized. However, new evidence is emerged on the importance of thyroid hormone in the response of the myocardium to ischaemic stress and cardiac remodelling following myocardial infarction. Based on this new information, this review highlights the role of thyroid hormone in myocardial ischaemia and cardiac remodelling, the possible underlying mechanisms and the potential therapeutic implications. Thyroid hormone or analogs may prove new therapeutic agents for treating ischaemic heart disease.

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