JAK2V617F: you can't have too much
- PMID: 18434961
- PMCID: PMC2288710
- DOI: 10.1182/blood-2008-01-133322
JAK2V617F: you can't have too much
Abstract
In this issue of Blood, Tiedt and colleagues use transgenic and retroviral models to demonstrate that the expression level of JAK2V617F plays an important role in determining myeloproliferative disease (MPD) phenotype.
Conflict of interest statement
Conflict-of-interest disclosure: The author declares no competing financial interests. ■
Comment on
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Ratio of mutant JAK2-V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice.Blood. 2008 Apr 15;111(8):3931-40. doi: 10.1182/blood-2007-08-107748. Epub 2007 Dec 26. Blood. 2008. PMID: 18160670
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