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Case Reports
. 2008 May;14(5):814-6.
doi: 10.3201/eid1405.070863.

Naturally acquired human Plasmodium knowlesi infection, Singapore

Oon Tek Ng  1 , Eng Eong Ooi, Cheng Chuan Lee, Piao Jarrod Lee, Lee Ching Ng, Sze Wong Pei, Tian Ming Tu, Jin Phang Loh, Yee Sin Leo
Affiliations
Case Reports

Naturally acquired human Plasmodium knowlesi infection, Singapore

Oon Tek Ng et al. Emerg Infect Dis. 2008 May.

Abstract

We report a case of naturally acquired Plasmodium knowlesi in Singapore, a malaria-free country. Diagnosis was confirmed by PCR with validated species-specific primers. In industrialized countries, free-ranging primates are a potential source of P. knowlesi human infection. P. knowlesi infection is a differential diagnosis of febrile illness acquired in Singapore.

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Figures

Figure 1
Figure 1
Patient’s temperature chart showing fever spikes 24 h apart at approximately 7 PM daily (red arrow). The black arrow denotes 38°C, and each blue arrow denotes a difference of 1°C from the neighboring arrow.
Figure 2
Figure 2
Phylogenetic trees comparing our case sample (denoted as SingPk1) with other Plasmodium species, based on SSU rRNA (A) and csp (B) sequences. Species and sequences used were selected to match those previously reported (5). Figures on the branches are bootstrap percentages based on 1,000 replicates, and only those above 80% are shown. GenBank accession numbers are in parentheses.
See this image and copyright information in PMC

References

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