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. 2008 Jul;52(7):2647-52.
doi: 10.1128/AAC.01398-07. Epub 2008 Apr 28.

In vitro activity of telavancin against resistant gram-positive bacteria

Kevin M Krause  1 , Marika Renelli, Stacey Difuntorum, Terry X Wu, Dmitri V Debabov, Bret M Benton
Affiliations

In vitro activity of telavancin against resistant gram-positive bacteria

Kevin M Krause et al. Antimicrob Agents Chemother. 2008 Jul.

Abstract

The in vitro activity of telavancin was tested against 743 predominantly antimicrobial-resistant, gram-positive isolates. Telavancin was highly active against methicillin-resistant staphylococci (MIC(90), 0.5 to 1 microg/ml), streptococci (all MICs, < or =0.12 microg/ml), and VanB-type enterococci (all MICs, < or =2 microg/ml). Time-kill studies demonstrated the potent bactericidal activity of telavancin.

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Figures

FIG. 1.
FIG. 1.
Distribution of telavancin MICs against VRE. Filled bars, VanB-type isolates; open bars, VanA-type isolates.
See this image and copyright information in PMC

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