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. 1976 Jul;3(7):1647-58.
doi: 10.1093/nar/3.7.1647.

"Fingerprinting" high molecular weight RNA by two-dimensional gel electrophoresis: application to poliovirus RNA

Y F Lee, E Wimmer
Free PMC article

"Fingerprinting" high molecular weight RNA by two-dimensional gel electrophoresis: application to poliovirus RNA

Y F Lee et al. Nucleic Acids Res. 1976 Jul.
Free PMC article

Abstract

Conditions are described under which complete RNase T1 digests of high molecular weight RNA can be separated into numerous components by two-dimensional gel electrophoresis. Small and large oligonucleotides (n = 1 - 2c0) can be resolved without losses. The procedure yields fingerprints which are diagnostic for a particular species of RNA and an index of its purity as will be shown for the genomes of poliovirus type 1 and 2.

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References

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