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Case Reports
. 1991 Oct;41(10):1541-4.
doi: 10.1212/wnl.41.10.1541.

Subacute, reversible motor neuron disease

T Tucker  1 , R B Layzer, R G Miller, D Chad
Affiliations
Case Reports

Subacute, reversible motor neuron disease

T Tucker et al. Neurology. 1991 Oct.

Abstract

Four patients with a clinical syndrome closely resembling amyotrophic lateral sclerosis recovered completely, without treatment, 5 to 12 months after onset. Electrodiagnostic tests revealed acute and chronic denervation, with normal motor and sensory nerve conduction studies. The CSF was normal, and tests for paraproteinemia, heavy metal intoxication, and systemic illness were negative. Although such cases are rare, the possibility of spontaneous recovery should always be considered when counseling patients with suspected ALS.

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Comment in

  • Reversible motor neuron disease.
    Grisold W, Drlicek M, Zifko U. Grisold W, et al. Neurology. 1992 Nov;42(11):2229; author reply 2230. doi: 10.1212/wnl.42.11.2229. Neurology. 1992. PMID: 1296615 No abstract available.
  • Reversible motor neuron disease.
    Hesselink JM. Hesselink JM. Neurology. 1992 Nov;42(11):2229-30. doi: 10.1212/wnl.42.11.2229-a. Neurology. 1992. PMID: 1436553 No abstract available.

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