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. 2008 Jun;63(2):83-6.
doi: 10.1007/s11130-008-0075-y. Epub 2008 Apr 29.

A carotenoid algal preparation containing phytoene and phytofluene inhibited LDL oxidation in vitro

Aviv Shaish  1 , Ayelet Harari, Yehuda Kamari, Etienne Soudant, Dror Harats, Ami Ben-Amotz
Affiliations

A carotenoid algal preparation containing phytoene and phytofluene inhibited LDL oxidation in vitro

Aviv Shaish et al. Plant Foods Hum Nutr. 2008 Jun.

Abstract

The antioxidative effect of the carotenoids phytoene and phytofluene in biological systems has not yet been studied. We therefore sought to investigate the effect of these carotenoids, isolated from the alga Dunaliella bardawil, in a biological system and used the in vitro low density lipoprotein (LDL) oxidation method to assay their antioxidative effects. We found that similar to beta-carotene and alpha-tocopherol, a carotenoid algal preparation containing phytoene and phytofluene inhibited LDL oxidation. These findings and the presence of phytoene and phytofluene in human tissues suggest that they can be part of the defense system against oxidative stress.

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