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Comparative Study
. 2008 Jun;15(6):1031-3.
doi: 10.1128/CVI.00424-07. Epub 2008 Apr 30.

Evaluation of seven tests for diagnosis of human brucellosis in an area where the disease is endemic

M Concepción Gómez  1 , José A Nieto, Carmen Rosa, Paloma Geijo, M Angeles Escribano, Amparo Muñoz, Clara López
Affiliations
Comparative Study

Evaluation of seven tests for diagnosis of human brucellosis in an area where the disease is endemic

M Concepción Gómez et al. Clin Vaccine Immunol. 2008 Jun.

Abstract

The results of seven serologic tests for diagnosis of human brucellosis were evaluated. The titrated Rose Bengal test, microagglutination test, microtiter-adapted Coombs test, and immunocapture-agglutination test (Brucellacapt) were positive for all sera from patients with acute brucellosis. The immunoglobulin G (IgG), IgM, and IgA commercial enzyme immunoassays (ELISAs) failed to show specific antibodies in 3 patients, 10 patients, and 1 patient, respectively. The sensitivity of ELISA is not higher than that of conventional tests.

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References

    1. Al Skait, M. A. 1999. Seroepidemiological survey of brucellosis antibodies in Saudi Arabia. Ann. Saudi Med. 19:219-222. - PubMed
    1. Araj, G. F., A. R. Lulu, M. Y. Mustafa, and M. I. Khateeb. 1986. Evaluation of ELISA in the diagnosis of acute and chronic brucellosis in human beings. J. Hyg. 97:457-469. - PMC - PubMed
    1. Bettelheim, K. A., W. J. Maskill, and J. Pearce. 1983. Comparison of standard tube and microagglutination techniques for determining Brucella antibodies. J. Hyg. 90:33-39. - PMC - PubMed
    1. Cooper, C. W. 1992. Prevalence of antibody to Brucella in asymptomatic well individuals in Saudi Arabia. J. Trop. Med. Hyg. 95:140-142. - PubMed
    1. Díaz, R., and I. Moriyon. 1989. Laboratory techniques in the diagnosis of human brucellosis, p. 73-83. In E. J. Young and M. J. Corbel (ed.), Brucellosis: clinical and laboratory aspects. CRC Press, Boca Raton, FL.

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