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Review
. 2008 Jul;51(7):1111-4.
doi: 10.1007/s00125-008-1027-7. Epub 2008 May 1.

The proposed terminology 'A(1c)-derived average glucose' is inherently imprecise and should not be adopted

Z T Bloomgarden  1 , S E Inzucchi, E Karnieli, D Le Roith
Affiliations
Review

The proposed terminology 'A(1c)-derived average glucose' is inherently imprecise and should not be adopted

Z T Bloomgarden et al. Diabetologia. 2008 Jul.

Abstract

The proposed use of a more precise standard for glycated (A(1c)) and non-glycated haemoglobin would lead to an A(1c) value, when expressed as a percentage, that is lower than that currently in use. One approach advocated to address the potential confusion that would ensue is to replace 'HbA(1c)' with a new term, 'A(1c)-derived average glucose.' We review evidence from several sources suggesting that A(1c) is, in fact, inherently imprecise as a measure of average glucose, so that the proposed terminology should not be adopted.

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References

    1. J Clin Pathol. 2004 Apr;57(4):346-9 - PubMed
    1. Diabetes Care. 2003 Jan;26(1):163-7 - PubMed
    1. Clin Chem Lab Med. 2007;45(8):996-9 - PubMed
    1. N Engl J Med. 2005 Dec 22;353(25):2643-53 - PubMed
    1. Diabetes Care. 2004 Jun;27(6):1259-64 - PubMed

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