What is the mechanism underlying treatment of pain by systemic application of lidocaine?
- PMID: 18455311
- DOI: 10.1016/j.pain.2008.04.001
What is the mechanism underlying treatment of pain by systemic application of lidocaine?
Comment on
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C-fiber spontaneous discharge evoked by chronic inflammation is suppressed by a long-term infusion of lidocaine yielding nanogram per milliliter plasma levels.Pain. 2008 Jul;137(1):218-228. doi: 10.1016/j.pain.2008.02.018. Epub 2008 Apr 18. Pain. 2008. PMID: 18395983
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- Blenk KH, Häbler HJ, Jänig W. Neomycin and gadolinium applied to an L5 spinal nerve lesion prevent mechanical allodynia-like behaviour in rats. Pain. 1997;70:155-165.
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