Role of cholinoceptors recycling in short-term potentiation of cholinosensitivity of command neurons in edible snail
- PMID: 18457013
- DOI: 10.1007/s10517-007-0309-2
Role of cholinoceptors recycling in short-term potentiation of cholinosensitivity of command neurons in edible snail
Abstract
Exocytosis inhibitor Exo 1, dynamin inhibitory peptide (inhibitor of endocytosis), and colchicine disturb short-term potentiation of cholinosensitivity of defensive behavior command neurons in edible snail induced by rhythmic electrical orthodromic stimulation. We hypothesize that the short-term potentiation of cholinosensitivity in the extra-synaptic membrane develops due to incorporation of extra cholinoceptors into neuron plasmalemma as a result of enhanced recycling of the internalized cholinoceptors with participation of microtubules.
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