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Review
. 2008 Apr;73(4):393-405.
doi: 10.1134/s0006297908040032.

Mammalian galectins: structure, carbohydrate specificity, and functions

E M Rapoport  1 , O V Kurmyshkina, N V Bovin
Affiliations
Review

Mammalian galectins: structure, carbohydrate specificity, and functions

E M Rapoport et al. Biochemistry (Mosc). 2008 Apr.

Abstract

Galectins are a family of beta-galactoside binding lectins, homological by a sequence of the carbohydrate-binding site. In this review literature data about structure and carbohydrate specificity of galectins are discussed. The role of galectins in the regulation of cell adhesion in immune response, inflammation, and cancer progression is considered.

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