Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Practice Guideline
. 2008 Jun;22(3):313-23.
doi: 10.1007/s00482-008-0676-2.

[Pharmacological treatment of fibromyalgia syndrome]

[Article in German]
C Sommer  1 , W Häuser, M Berliner, W Brückle, S Ehlers, K Mönkemöller, B Moradi, F Petzke, N Uçeyler, R Wörz, E Winter, D O Nutzinger
Affiliations
Practice Guideline

[Pharmacological treatment of fibromyalgia syndrome]

[Article in German]
C Sommer et al. Schmerz. 2008 Jun.

Abstract

Background: An interdisciplinary guideline for the treatment of fibromyalgia syndrome (FMS) and chronic widespread pain (CWP) was developed in cooperation with ten German medical and psychological associations and two patients' self-help organizations.

Methods: Using the Cochrane Collaboration Reviews (1993-12/2006), Medline (1980-2006), PsychInfo (1966-12/2006), and Scopus (1980-12/ 2006) a systematic literature search was performed, which included all randomised controlled trials (RCT) evaluating multicomponent therapy in FMS and CWP. Levels of evidence were assigned according to the classification system of the Oxford Centre for Evidence-Based Medicine. The strength of recommendation was graded according to the German program for disease management guidelines. Consensus was achieved using a multi-step nominal group procedure.

Results: The short-term use of amitriptyline is strongly recommended (grade A) and the short-term use of fluoxetine und duloxetine is recommended (grade B).

Conclusions: The recommendations regarding pharmacological treatment of FMS are limited by the short duration of the RCT, the lack of follow-ups and absence of cost-effectiveness studies.

PubMed Disclaimer

References

    1. J Rheumatol. 2004 Apr;31(4):783-4 - PubMed
    1. Arthritis Rheum. 1988 Dec;31(12):1535-42 - PubMed
    1. Am J Med. 2002 Feb 15;112(3):191-7 - PubMed
    1. Arthritis Rheum. 1986 Nov;29(11):1371-7 - PubMed
    1. Arthritis Rheum. 2004 Sep;50(9):2974-84 - PubMed

Publication types

MeSH terms

LinkOut - more resources