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Comment
. 2008 May 8;2(5):408-10.
doi: 10.1016/j.stem.2008.04.006.

Open chromatin and hypertranscription in embryonic stem cells

Bryan M Turner  1
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Free article
Comment

Open chromatin and hypertranscription in embryonic stem cells

Bryan M Turner. Cell Stem Cell. .
Free article

Abstract

In this issue of Cell Stem Cell, Efroni et al. (2008) use tiling microarrays to reveal genome-wide hypertranscription in mouse embryonic stem cells (ESCs), including expression of normally silent, noncoding regions. Hypertranscription may reflect the unusual "open" structure of ESC chromatin.

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  • Global transcription in pluripotent embryonic stem cells.
    Efroni S, Duttagupta R, Cheng J, Dehghani H, Hoeppner DJ, Dash C, Bazett-Jones DP, Le Grice S, McKay RD, Buetow KH, Gingeras TR, Misteli T, Meshorer E. Efroni S, et al. Cell Stem Cell. 2008 May 8;2(5):437-47. doi: 10.1016/j.stem.2008.03.021. Cell Stem Cell. 2008. PMID: 18462694 Free PMC article.

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