A new elemanolide sesquiterpene lactone from Elephantopus scaber
- PMID: 18464077
- DOI: 10.1080/10286020801966526
A new elemanolide sesquiterpene lactone from Elephantopus scaber
Abstract
A new elemanolide sesquiterpene lactone, named elescaberin (1), together with two known compounds, namely, isodeoxyelephantopin (2) and deoxyelephantopin (3), was isolated from the whole plant of Elephantopus scaber. The structure of 1 was elucidated on the basis of spectroscopic analysis. All three compounds exhibited significant inhibitory activities against human SMMC-7721 liver cancer cells in vitro (IC(50) 8.18-14.08 micromol/l).
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