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Comment
. 2008 May 15;111(10):4836-7.
doi: 10.1182/blood-2008-02-135988.

Where the Epo cells are

Constance Tom Noguchi  1
Affiliations
Comment

Where the Epo cells are

Constance Tom Noguchi. Blood. .

Abstract

In this issue of Blood, Obara and colleagues report on their use of a GFP transgene to mark kidney Epo-producing cells in mice. These cells in the interstitial space express neuronal markers, and their number correlates with plasma Epo levels and increases with hypoxic induction.

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Conflict of interest statement

Conflict-of-interest disclosure: The author declares no competing financial interests. ■

Figures

None
Hypoxia has been found to increase the number of Epo-expressing cells. Peritubular interstitial cells (blue), with long projections between the proximal tubules (PT) formed by epithelial cells (EC), are induced to express Epo (green) by hypoxia or anemic stress. Illustration by Kenneth Probst.
See this image and copyright information in PMC

Comment on

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