Gastric ulcer treatment: cure of Helicobacter pylori infection without subsequent acid-suppressive therapy: is it effective?
- PMID: 18467903
- DOI: 10.1097/MEG.0b013e3282f427c8
Gastric ulcer treatment: cure of Helicobacter pylori infection without subsequent acid-suppressive therapy: is it effective?
Abstract
Whether it is a requirement to continue with anti-secretory therapy following anti-Helicobacter therapy in H. pylori positive gastric ulcers is an important question. As gastric ulcers tend to heal more slowly than duodenal ulcers, may be asymptomatic or only causing mild symptoms and success at curing H. pylori with current fist line therapies is 80% at best, clinicians will likely err on the side of caution and continue acid suppressive therapy to ensure healing of gastric ulcers. This is certainly recommended when dealing with bleeding ulcers.
Comment on
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Effect of esomeprazole triple therapy on eradication rates of Helicobacter pylori, gastric ulcer healing and prevention of relapse in gastric ulcer patients.Eur J Gastroenterol Hepatol. 2008 Jun;20(6):526-36. doi: 10.1097/MEG.0b013e3282f427ac. Eur J Gastroenterol Hepatol. 2008. PMID: 18467912 Clinical Trial.
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