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Case Reports
. 1991 Feb;41(2 ( Pt 1)):206-8.
doi: 10.1212/wnl.41.2_part_1.206.

Unusual amyloid polyneuropathy with predominant lumbosacral nerve roots and plexus involvement

J C Antoine  1 , A Baril, C Guettier, F G Barral, B Bady, P Convers, D Michel
Affiliations
Case Reports

Unusual amyloid polyneuropathy with predominant lumbosacral nerve roots and plexus involvement

J C Antoine et al. Neurology. 1991 Feb.

Abstract

We report a 25-year-old patient with a progressive asymmetric peripheral neuropathy of the distal lower limbs. Imaging studies showed enlargement of lumbosacral roots, plexus, and proximal sciatic nerve. Sacral plexus biopsy revealed amyloidosis associated with endoneurial edema. Immunohistochemistry with anti-prealbumin, serum amyloid A, and immunoglobulin light chain antisera failed to label the amyloid.

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