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. 1991 Jan 14;278(1):103-6.
doi: 10.1016/0014-5793(91)80094-j.

Hepatocyte swelling increases inositol 1,4,5-trisphosphate, calcium and cyclic AMP concentration but antagonizes phosphorylase activation by Ca2(+)-dependent hormones

A Baquet  1 , A J Meijer, L Hue
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Free article

Hepatocyte swelling increases inositol 1,4,5-trisphosphate, calcium and cyclic AMP concentration but antagonizes phosphorylase activation by Ca2(+)-dependent hormones

A Baquet et al. FEBS Lett. .
Free article

Abstract

Swelling of hepatocytes increases the concentration of inositol 1,4,5-trisphosphate, Ca2+ and cAMP, without activating glycogen phosphorylase. In these hepatocytes, the activation of phosphorylase by suboptimal concentrations of vasopressin or angiotensin II was partly antagonized.

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