AMPK and Raptor: matching cell growth to energy supply
- PMID: 18471972
- DOI: 10.1016/j.molcel.2008.04.012
AMPK and Raptor: matching cell growth to energy supply
Abstract
In a recent issue of Molecular Cell, Gwinn et al. (2008) suggest a novel mechanism by which AMPK signals to mTOR, and they provide new insight into how information about cellular energy status is fed into decisions about cell growth and proliferation.
Comment on
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AMPK phosphorylation of raptor mediates a metabolic checkpoint.Mol Cell. 2008 Apr 25;30(2):214-26. doi: 10.1016/j.molcel.2008.03.003. Mol Cell. 2008. PMID: 18439900 Free PMC article.
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