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. 1976;51(4):299-306.
doi: 10.1007/BF01317933.

Localisation on foot-and-mouth disease virus (FMDV) of an antigenic deficiency induced by passage in BHK cells

R H Meloen

Localisation on foot-and-mouth disease virus (FMDV) of an antigenic deficiency induced by passage in BHK cells

R H Meloen. Arch Virol. 1976.

Abstract

Passage of FMDV in BHK suspended cells was confirmed to induce an antigenic deficiency on the virion. By immunodiffusion experiments with complete virus, with trypsin-treated virus and with 12S virus fraction it was shown that the induced antigenic deficiency is located on the trypsin-removable part of the virion. These results were confirmed by absorption experiments.

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