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Comment
. 2008 May;14(5):642-4.
doi: 10.1016/j.devcel.2008.04.012.

Glucose restriction: longevity SIRTainly, but without building muscle?

Carles Cantó  1 , Johan Auwerx
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Glucose restriction: longevity SIRTainly, but without building muscle?

Carles Cantó et al. Dev Cell. 2008 May.
Free article

Abstract

The two metabolic sensors AMPK and SIRT1 take center stage as Fulco et al. reveal, in this issue of Developmental Cell, the signaling mechanism by which low glucose prevents the correct development of the myogenic program. These observations may hold some therapeutic promise against muscle wasting.

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