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Comment
. 2008 Jun;73(11):1211-3.
doi: 10.1038/ki.2008.117.

Plasma exchange for myeloma kidney: cast(s) away?

W F Clark  1 , A X Garg
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Free article
Comment

Plasma exchange for myeloma kidney: cast(s) away?

W F Clark et al. Kidney Int. 2008 Jun.
Free article

Abstract

Leung et al. (this issue) present a retrospective study of 40 patients. Observations in 14/40 led to the suggestion of restitution of plasma exchange for light-chain responsive, biopsy-proven myeloma kidney until a better randomized control trial (RCT) is constructed. A careful analysis of their study and a recent RCT suggest little difference in outcome between plasma exchange and control groups. The analysis supports restitution of a better RCT of plasma exchange for myeloma kidney rather than off-label use.

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