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. 2008 May;31(5):594-7.
doi: 10.1007/s12272-001-1198-1. Epub 2008 May 15.

In vitro hepatoprotective compounds from Suaeda glauca

Ren-Bo An  1 , Dong-Hwan Sohn, Gil-Saeng Jeong, Youn-Chul Kim
Affiliations

In vitro hepatoprotective compounds from Suaeda glauca

Ren-Bo An et al. Arch Pharm Res. 2008 May.

Abstract

Bioassay-guided fractionation of the MeOH extract of Suaeda glauca yielded four phenolic compounds, methyl 3,5-di-O-caffeoyl quinate (1) and 3,5-di-O-caffeoyl quinic acid (2), isorhamnetin 3-O-beta-D-galactoside (3), and quercetin 3-O-beta-D-galactoside (4). Compounds 1 and 2 were hepatoprotective against tacrine-induced cytotoxicity in human liver-derived Hep G2 cells with the EC(50) values of 72.7+/-6.2 and 117.2+/-10.5 microM, respectively. Silybin as a positive control showed an EC(50) value of 82.4+/-4.1 microM.

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