Genes and quadrupedal locomotion in humans

Comment

Nicholas Humphrey et al. Proc Natl Acad Sci U S A. 2008.

. 2008 May 27;105(21):E26.

doi: 10.1073/pnas.0802839105. Epub 2008 May 15.

No abstract available

Conflict of interest statement

The authors declare no conflict of interest.

Reply to Herz et al. and Humphrey et al.: Genetic heterogeneity of cerebellar hypoplasia with quadrupedal locomotion.
Ozcelik T, Akarsu N, Uz E, Caglayan S, Gulsuner S, Onat OE, Tan M, Tan U. Ozcelik T, et al. Proc Natl Acad Sci U S A. 2008 Jun 10;105(23):E32-3. doi: 10.1073/pnas.0804078105. Proc Natl Acad Sci U S A. 2008. PMID: 18544652 Free PMC article. No abstract available.

Mutations in the very low-density lipoprotein receptor VLDLR cause cerebellar hypoplasia and quadrupedal locomotion in humans.
Ozcelik T, Akarsu N, Uz E, Caglayan S, Gulsuner S, Onat OE, Tan M, Tan U. Ozcelik T, et al. Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4232-6. doi: 10.1073/pnas.0710010105. Epub 2008 Mar 7. Proc Natl Acad Sci U S A. 2008. PMID: 18326629 Free PMC article.

1. Ozcelik T, et al. Mutations in the very low-density lipoprotein receptor VLDLR cause cerebellar hypoplasia and quadrupedal locomotion in humans. Proc Natl Acad Sci USA. 2008;105:4232–4236. - PMC - PubMed
1. Türkmen S, et al. Cerebellar hypoplasia, with quadrupedal locomotion, caused by mutations in the very low density lipoprotein receptor gene. Eur J Hum Genet. 2008 Mar 26; doi: 10.1038/ejhg.2008.73. - DOI - PubMed
1. Humphrey N, Skoyles J, Keynes R. London: Centre for Philos of Nat and Soc Sci; 2005. Human hand-walkers: Five siblings who never stood up. Discussion paper. Available at http://eprints.lse.ac.uk/463.
1. Türkmen S, et al. Cerebellar hypoplasia and quadrupedal locomotion in humans as a recessive trait mapping to chromosome 17p. J Med Genet. 2006;43:461–464. - PMC - PubMed
1. Fletcher M. Life on all fours. Times Online. 2007 Oct 17; Available at www.timesonline.co.uk/tol/life_and_style/health/article2671426.ece.