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. 2008 Aug;15(8):869-71.
doi: 10.1111/j.1468-1331.2008.02173.x. Epub 2008 May 15.

Cardiovagal modulation upon postural change is altered in Huntington's disease

K J Bär  1 , M K Boettger, J Andrich, J T Epplen, F Fischer, J Cordes, M Koschke, M W Agelink
Affiliations

Cardiovagal modulation upon postural change is altered in Huntington's disease

K J Bär et al. Eur J Neurol. 2008 Aug.

Abstract

Background: Cardiac autonomic nervous system (ANS) dysfunction in Huntington's disease (HD) might affect both the sympathetic and parasympathetic branch of the ANS.

Results and conclusions: The pattern of linear heart rate variability we found in mid stage HD patients points towards a predominately reduced cardiovagal modulation compared with healthy subjects, which might influence HD patients' susceptibility for cardiovascular complications such as syncopes and cardiac arrhythmias.

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