doi: 10.1111/j.1468-1331.2008.02173.x.
Epub 2008 May 15.
Cardiovagal modulation upon postural change is altered in Huntington's disease
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- PMID: 18484985
- DOI: 10.1111/j.1468-1331.2008.02173.x
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Cardiovagal modulation upon postural change is altered in Huntington's disease
Eur J Neurol.
2008 Aug.
Abstract
Background: Cardiac autonomic nervous system (ANS) dysfunction in Huntington's disease (HD) might affect both the sympathetic and parasympathetic branch of the ANS.
Results and conclusions: The pattern of linear heart rate variability we found in mid stage HD patients points towards a predominately reduced cardiovagal modulation compared with healthy subjects, which might influence HD patients' susceptibility for cardiovascular complications such as syncopes and cardiac arrhythmias.
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