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Review
. 2008 Jun;35(2):329-44, vii.
doi: 10.1016/j.pop.2008.01.008.

Chronic kidney disease and its complications

Robert Thomas  1 , Abbas Kanso, John R Sedor
Affiliations
Review

Chronic kidney disease and its complications

Robert Thomas et al. Prim Care. 2008 Jun.

Abstract

Chronic kidney disease (CKD) is a complex disease affecting more than 20 million individuals in the United States. Progression of CKD is associated with a number of serious complications, including increased incidence of cardiovascular disease, hyperlipidemia, anemia, and metabolic bone disease. CKD patients should be assessed for the presence of these complications and receive optimal treatment to reduce their morbidity and mortality. A multidisciplinary approach is required to accomplish this goal.

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Figures

Figure 1
Figure 1
Interplay of processes secondary to chronic kidney disease leading to cardiovascular disease and death. Red arrows: Pathogenetic pathways; black arrow: Feedback loop; kidney disease worsened by heart failure
See this image and copyright information in PMC

References

    1. Coresh J, Selvin E, Stevens LA, et al. Prevalence of chronic kidney disease in the United States. Jama-Journal of the American Medical Association. 2007;298:2038–2047. - PubMed
    1. KDOQI Clinical Practice Guidelines and Clinical Practice Recommendations for Anemia in Chronic Kidney Disease. Am.J.Kidney Dis. 2006;47:S11–S145. - PubMed
    1. Levey AS, Eckardt KU, Tsukamoto Y, et al. Definition and classification of chronic kidney disease: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO) Kidney Int. 2005;67:2089–2100. - PubMed
    1. Coresh J, Astor BC, Greene T, et al. Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey. American Journal of Kidney Diseases. 2003;41:1–12. - PubMed
    1. Hsu CY, Vittinghoff E, Lin F, et al. The incidence of end-stage renal disease is increasing faster than the prevalence of chronic renal insufficiency. Ann.Intern.Med. 2004;141:95–101. - PubMed