doi: 10.1210/jcem-45-2-367.
Cimetidine, an H2-antihistamine, stimulates prolactin secretion in man
- PMID: 18488
- DOI: 10.1210/jcem-45-2-367
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Cimetidine, an H2-antihistamine, stimulates prolactin secretion in man
J Clin Endocrinol Metab.
1977 Aug.
Abstract
Intravenous administration of cimetidine, a histamine (H2) receptor antagonist, provoked an immediate 2 to 3-fold rise in serum prolactin concentrations in 8 normal men; serum thyrotropin, growth hormone, thyroxine, and triiodothyronine were not significantly affected. Diphenhydramine, an H1-antagonist, was without effect on any of the hormones measured. The results suggest that histamine may have an important function in the regulation of prolactin secretion in man.
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